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Research
Mandelic Acid & Skin Conditions
The latest research and development from NuCèlle® is now focused on the little heard of but highly effective Mandelic Acid. Studies are now being conducted on the efficacy of this acid compared to other alpha hydroxy acids.
Preliminary studies show Mandelic Acid to be less sensitizing and remarkably effective in alleviating such skin conditions as Melasma and hyperpigmentation.
Another noticeable benefit is a smoother, clearer, and less lined complexion as described in an article, “Treatment of Melasma Using Combination Intense Pulsed Light and Topical Therapy,” presented at the Skin and Aging Conference in San Francisco, California in January of 1999, along with an instructional lecture given by Dr. Theresa A. Scholz.
Mandelic Acid Works!
Mark Taylor, M.D., of Salt Lake City, Utah, first introduced Mandelic Acid to the NuCèlle® team in late 1996. Dr. Taylor has been testing and using the Mandelic Marine Complex® formulations since 1995. During the course of his clinical trials, he discovered that he was able to use the Mandelic Acid safely on pigmented skin. He also discovered that it caused less sensitivity, when compared to other alpha hydroxy acids. His research is highlighted in the article, “Summary of Mandelic Acid for the Improvement of Skin Conditions,” published in Cosmetic Dermatology, June 1999 issue.
In a letter directed to NuCèlle®, Dr. Taylor described his open and closed technique for post-operative care following laser resurfacing. The regimen, which Dr. Taylor found most effective, is the foundation for the Five Step Program.
The Proof
During the summer of 1999, NuCèlle® commissioned the California Skin Research Institute (CSRI) to conduct an independant study of the Mandelic Marine Complex® formulations used for the treatment of facial pigmentary lesions, acne lesions and blemishes, and facial lines/wrinkles as a cosmetic skin conditioning regimen. After 6 weeks of treatment, the reported summary indicated that 81% of subjects rated the system as excellent and very good, while 75% of subjects exhibited significant, overall improvement in skin texture.
The analysis of the D-Squame Data along with the Novameter Data indicated a significant overall increase in moisturization and smoothness of the skin.
*Note: Study subjects were instructed not to use any facial conditioning products other than the test articles during the study.[Click here for a summary of this study, CSRI #99-016 by Dr. Robert A. Harper, Ph. D.]